With regard to resume format, you may consider switching to a "functional" format rather than the typical reverse chronological format used. This format prioritizes skills and traits over direct experience, and can be a useful format for those switching careers that may not have direct experience in their target industry.
In terms of which skills to highlight you can do some research for job postings of the type of role you're targeting, then tailor your resume to present your skills and experience accordingly.
Finally, you may consider engaging a recruiter. They can advocate for your skills, personality, etc... and can be a key tool in getting you beyond the automated resume scanning software many companies use.