I do think that a layout has a lot to do with a good resume.
My personal preferance is to use a few different, fun yet readable fonts for different parts of the resume. For example, my name and address are in Monotype Corsiva, which is one of my favorite fonts. I then have specific bullets for each show I've done, with of course the job, director, venue, and location of the show. The bullets are not the regular dots, but these cool triangle looking things that are very professional but also a little more fun than just the black dots. All of my headings are in the same font, such as Show Experience, Special Skills, Education, etc., and then the information listed under each heading are also all in the same font. It looks very well put together, but adds my own personal flair to the page. I think that's really important, regardless of what design you use. Make sure it describes you while looking well put together at the same time.
One resume I have seen that caught my eye had the Name and Personal Info (Address, Phone #, etc.) and then had two clip art pictures on either side, one of the drama masks and one of a headset. It was very nicely laid out so that the pictures did not overdo it, but brought a nice flair to the page so that it definitely stood out in a crowd. You might consider doing something like that if it strikes you.
Look at the different bullet/numbering styles you can do, look at table style resumes, fonts, sizes, etc. If you go on SMNet Resume Browser and look at some of the different resumes, it definitely helps to give you an idea of the variety of things that you can do. I think in the end it's all up to your own personal preferances and how you want people to see you on paper.
I would of course be happy to share my resume with you if you would like to look at my own personal style and see yet another way to do things.