I just finished directing this last month.
Pre-set needs to be photographically precise. Suzy cannot "search" for a prop that is mis-placed. And there's lots of minutia to keep track of (door keys, cigarettes, etc.)
We decided NOT to do the fake knife bit, as it was more work than would pay off in the scene.
Smoking was an issue. We tried fake cigarettes, but it was definitely a compromise, and we never really achieved the moment of the cigarette burning in the ashtray effectively. And it's not like you can really write the smoking out of it, since Sam's smoke is a plot device and Roat's smoke is so indicative of his character.
Another thing is the mess in Act II created by Mike and Suzy "searching" the apartment during intermission. It's a delicate balance between creating clutter while avoiding "blind" actor traps.
The end of II.1 is a calling challenge, as Gloria and Suzy pull fuses and break hallway lights.
Good Luck!