If there's a lot of things going on, I recommend one column of text per page. The system that I use, I have my page of text on the right, and then on the left (the back of the previous page) I divide into two columns, one for blocking and one for cue notes. I put a circled number in the text at the point where a bit of blocking happens, and then right down the actual blocking in the column to the left. For me, it leaves the page of text clear for when I put my cues in, so there's less clutter. I'll put the actual cues, what I call, in the script, but then 'cliff notes' for myself in the other column on the left hand page. This way I can write down what is happening in the light cue, what the sound cue is and how long it is, etc., etc.. Again, more detailed info that would just start to clutter up my page of text.
My style is just one of many different prompt books styles out there, as varied as the stage managers who use them. If you have any stage management books available for you to look at, they also will give ideas for organizing a prompt book.
My advice on the script, if you can get an online copy made out, and get one to your director & tech staff early (before rehearsal starts), then that sounds like a good way to go. If you can't beat them to the punch, beware of how different your script is from the director's - or you could spend half your rehearsal time trying to figure out where the director's page 17 is in your script.
If the director and the tech staff are using actual books, then you might be stuck sitting and copying the script page for page from that book, so that you're all on 'the same page'.
-Centaura